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p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

Activation of the p38 MAP kinase pathways is crucial for the adaptation of mammalian cells to changes in the osmolarity of the environment. Here we identify SAP97/hDlg, the mammalian homologue of the Drosophila tumour suppressor Dlg, as a physiological substrate for the p38γ MAP kinase (SAPK3/p38γ)...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Sabio, Guadalupe, Arthur, James Simon Campbell, Kuma, Yvonne, Peggie, Mark, Carr, Julia, Murray-Tait, Vicky, Centeno, Francisco, Goedert, Michel, Morrice, Nicholas A, Cuenda, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15729360/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600578
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