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Perspectives of HER2-targeting in gastric and esophageal cancer

INTRODUCTION: The blockade of HER2 signaling has significantly improved the outlook for esophagogastric cancer patients. However, targeting HER2 still remains challenging due to complex biology of this receptor in gastric and esophageal cancers. AREAS COVERED: Here, we review complex HER2 biology, c...

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Detalhes bibliográficos
Publicado no:Expert Opin Investig Drugs
Main Authors: Gerson, James N, Skiara, Sam, Denlinger, Crystal S., Astsaturov, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563845/
https://ncbi.nlm.nih.gov/pubmed/28387541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2017.1315406
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