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Experimental models of neuromyelitis optica: current status, challenges and future directions

Neuromyelitis optica (NMO) is a recurrent inflammatory disease that predominantly attacks the opticnerves and spinal cord. NMO-IgG, the specific autoantibody present in the vast majority of NMO patients, targets the astrocytic water channel protein aquaporin 4 (AQP4), and differentiates NMO from mul...

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Bibliographic Details
Published in:Neurosci Bull
Main Authors: Li, Minshu, Yan, Yaping
Format: Artigo
Language:Inglês
Published: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563723/
https://ncbi.nlm.nih.gov/pubmed/26109280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-015-1552-6
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