SipA Activation of Caspase-3 Is a Decisive Mediator of Host Cell Survival at Early Stages of Salmonella enterica Serovar Typhimurium Infection

Salmonella invasion protein A (SipA) is a dual-function effector protein that plays roles in both actin polymerization and caspase-3 activation in intestinal epithelial cells. To date its function in other cell types has remained largely unknown despite its expression in multiple cell types and its...

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Publicado en:Infect Immun
Autores principales: McIntosh, Anne, Meikle, Lynsey M., Ormsby, Michael J., McCormick, Beth A., Christie, John M., Brewer, James M., Roberts, Mark, Wall, Daniel M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563584/
https://ncbi.nlm.nih.gov/pubmed/28630067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00393-17
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