Degradation of Incretins and Modulation of Blood Glucose Levels by Periodontopathic Bacterial Dipeptidyl Peptidase 4

Severe periodontitis is known to aggravate diabetes mellitus, though molecular events related to that link have not been fully elucidated. Porphyromonas gingivalis, a major pathogen of periodontitis, expresses dipeptidyl peptidase 4 (DPP4), which is involved in regulation of blood glucose levels by...

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Vydáno v:Infect Immun
Hlavní autoři: Ohara-Nemoto, Yuko, Nakasato, Manami, Shimoyama, Yu, Baba, Tomomi T., Kobayakawa, Takeshi, Ono, Toshio, Yaegashi, Takashi, Kimura, Shigenobu, Nemoto, Takayuki K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563571/
https://ncbi.nlm.nih.gov/pubmed/28630069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00277-17
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