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Identification and Characterization of Two Klebsiella pneumoniae lpxL Lipid A Late Acyltransferases and Their Role in Virulence

Klebsiella pneumoniae causes a wide range of infections, from urinary tract infections to pneumonia. The lipopolysaccharide is a virulence factor of this pathogen, although there are gaps in our understanding of its biosynthesis. Here we report on the characterization of K. pneumoniae lpxL, which en...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Mills, Grant, Dumigan, Amy, Kidd, Timothy, Hobley, Laura, Bengoechea, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563558/
https://ncbi.nlm.nih.gov/pubmed/28652313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00068-17
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