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Atorvastatin enhances radiosensitivity in hypoxia-induced prostate cancer cells related with HIF-1α inhibition

Hypoxia could enhance radioresistance in prostate cancer cells through up-regulating HIF-1α, which could be inhibited by statins in several cancer cells. However, this effect of statins in prostate cancer remains unclear. In the present study, we aim to investigate the effect of atorvastatin on HIF-...

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Bibliografiska uppgifter
I publikationen:Biosci Rep
Huvudupphovsmän: Chen, Bin, Zhang, Minguang, Xing, Dongwei, Feng, Yu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press Ltd. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563539/
https://ncbi.nlm.nih.gov/pubmed/28760843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170340
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