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Estimation of flux ratios without uptake or release data: application to serine and methionine metabolism
Model-based metabolic flux analysis (MFA) using isotope-labeled substrates has provided great insight into intracellular metabolic activities across a host of organisms. One challenge with applying MFA in mammalian systems, however, is the need for absolute quantification of nutrient uptake, biomass...
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| Publicado no: | Metab Eng |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563485/ https://ncbi.nlm.nih.gov/pubmed/28232235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2017.02.005 |
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