Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A

BACKGROUND: BAY 81-8973 is a full-length, unmodified, recombinant human factor VIII (FVIII) for the treatment of hemophilia A. OBJECTIVE: The aim of this study was to compare the pharmacokinetic (PK) profile of BAY 81-8973 with antihemophilic factor (recombinant) plasma/albumin-free method (rAHF-PFM...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Shah, Anita, Solms, Alexander, Garmann, Dirk, Katterle, Yvonne, Avramova, Verzhiniya, Simeonov, Stanislav, Lissitchkov, Toshko
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563350/
https://ncbi.nlm.nih.gov/pubmed/28005225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-016-0492-2
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