Parietal white matter lesions in Alzheimer’s disease are associated with cortical neurodegenerative pathology, but not with small vessel disease

Cerebral white matter lesions (WML) encompass axonal loss and demyelination, and the pathogenesis is assumed to be small vessel disease (SVD)-related ischemia. However, WML may also result from the activation of Wallerian degeneration as a consequence of cortical Alzheimer’s disease (AD) pathology,...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: McAleese, Kirsty E., Walker, Lauren, Graham, Sophie, Moya, Elisa L. J., Johnson, Mary, Erskine, Daniel, Colloby, Sean J., Dey, Madhurima, Martin-Ruiz, Carmen, Taylor, John-Paul, Thomas, Alan J., McKeith, Ian G., De Carli, Charles, Attems, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563333/
https://ncbi.nlm.nih.gov/pubmed/28638989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1738-2
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