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Therapeutic Antibodies against Intracellular Tumor Antigens

Monoclonal antibodies are among the most clinically effective drugs used to treat cancer. However, their target repertoire is limited as there are relatively few tumor-specific or tumor-associated cell surface or soluble antigens. Intracellular molecules represent nearly half of the human proteome a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Trenevska, Iva, Li, Demin, Banham, Alison H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563323/
https://ncbi.nlm.nih.gov/pubmed/28868054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01001
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