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Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in glio-vascular cells
Inhibition of the 90 kDa heat-shock protein (HSP90) leads to upregulation of the 70 kDa inducible heat shock protein (HSP70). HSP70 has previously been shown to be neuroprotective and anti-inflammatory. Geldanamycin (GA) and other HSP90 inhibitors have emerged as promising therapeutic agents in canc...
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| Publicado no: | Glia |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563260/ https://ncbi.nlm.nih.gov/pubmed/25802219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22811 |
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