Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins

Neuroligin-neurexin (NL-NRX) complexes are fundamental synaptic organizers in the central nervous system. An accurate spatial and temporal control of NL-NRX signaling is crucial to balance excitatory and inhibitory neurotransmission, and perturbations are linked with neurodevelopmental and psychiatr...

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Publicado en:Neuron
Main Authors: Elegheert, Jonathan, Cvetkovska, Vedrana, Clayton, Amber J., Heroven, Christina, Vennekens, Kristel M., Smukowski, Samuel N., Regan, Michael C., Jia, Wanyi, Smith, Alexandra C., Furukawa, Hiro, Savas, Jeffrey N., de Wit, Joris, Begbie, Jo, Craig, Ann Marie, Aricescu, A. Radu
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563082/
https://ncbi.nlm.nih.gov/pubmed/28817804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.07.040
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