Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins

Neuroligin-neurexin (NL-NRX) complexes are fundamental synaptic organizers in the central nervous system. An accurate spatial and temporal control of NL-NRX signaling is crucial to balance excitatory and inhibitory neurotransmission, and perturbations are linked with neurodevelopmental and psychiatr...

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發表在:Neuron
Main Authors: Elegheert, Jonathan, Cvetkovska, Vedrana, Clayton, Amber J., Heroven, Christina, Vennekens, Kristel M., Smukowski, Samuel N., Regan, Michael C., Jia, Wanyi, Smith, Alexandra C., Furukawa, Hiro, Savas, Jeffrey N., de Wit, Joris, Begbie, Jo, Craig, Ann Marie, Aricescu, A. Radu
格式: Artigo
語言:Inglês
出版: Cell Press 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563082/
https://ncbi.nlm.nih.gov/pubmed/28817804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.07.040
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