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A pivotal role of calcineurin signaling in development and maturation of postnatal cerebellar granule cells

Primary culture of postnatal cerebellar granule cells provides a model system that recapitulates many molecular events of developing granule cells in vivo. Depolarization of cultured granule cells increases intracellular Ca(2+) and activates Ca(2+)/calmodulin-dependent calcineurin (CaN) phosphatase....

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Bibliografiske detaljer
Main Authors: Sato, Masaaki, Suzuki, Kazunori, Yamazaki, Hiroshi, Nakanishi, Shigetada
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC556295/
https://ncbi.nlm.nih.gov/pubmed/15809415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501972102
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