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Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase

Contact-dependent growth inhibition (CDI) is a wide-spread mechanism of inter-bacterial competition. CDI(+) bacteria deliver CdiA-CT toxins into neighboring bacteria and produce specific immunity proteins that protect against self-intoxication. The CdiA-CT toxin from uropathogenic Escherichia coli 5...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Benoni, Roberto, Beck, Christina M., Garza-Sánchez, Fernando, Bettati, Stefano, Mozzarelli, Andrea, Hayes, Christopher S., Campanini, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562914/
https://ncbi.nlm.nih.gov/pubmed/28821763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09022-6
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