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Interplay between maternal Slc6a4 mutation and prenatal stress: a possible mechanism for autistic behavior development

The low activity allele of the maternal polymorphism, 5HTTLPR, in the serotonin transporter, SLC6A4, coupled with prenatal stress is reported to increase the risk for children to develop autism spectrum disorder (ASD). Similarly, maternal Slc6a4 knock-out and prenatal stress in rodents results in of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sjaarda, Calvin P., Hecht, Patrick, McNaughton, Amy J. M., Zhou, Audrina, Hudson, Melissa L., Will, Matt J., Smith, Garth, Ayub, Muhammad, Liang, Ping, Chen, Nansheng, Beversdorf, David, Liu, Xudong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562880/
https://ncbi.nlm.nih.gov/pubmed/28821725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07405-3
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