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Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice

The salivary gland is rhythmically controlled by sympathetic nerve activation from the suprachiasmatic nucleus (SCN), which functions as the main oscillator of circadian rhythms. In humans, salivary IgA concentrations reflect circadian rhythmicity, which peak during sleep. However, the mechanisms co...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wada, Misaki, Orihara, Kanami, Kamagata, Mayo, Hama, Koki, Sasaki, Hiroyuki, Haraguchi, Atsushi, Miyakawa, Hiroki, Nakao, Atsuhito, Shibata, Shigenobu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562870/
https://ncbi.nlm.nih.gov/pubmed/28821839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09438-0
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