Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD

Contactin-4 (CNTN4) is a complex cell adhesion molecule (CAM) localized at neuronal membranes, playing a key role in maintaining the mechanical integrity and signaling properties of the synapse. CNTN4 consists of six immunoglobulin C2 type (IgC2) domains and four fibronectin type III (FnIII) domains...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mikulska-Ruminska, Karolina, Kulik, Andrej J., Benadiba, Carine, Bahar, Ivet, Dietler, Giovanni, Nowak, Wieslaw
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562865/
https://ncbi.nlm.nih.gov/pubmed/28821864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09482-w
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