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Unconventional MAPK-GSK-3β Pathway Behind Atypical Epithelial-Mesenchymal Transition In Hepatocellular Carcinoma

We recently reported an atypical epithelial mesenchymal transition (EMT) in human hepatoma cell culture Huh7.5, which was non-responsive to the canonical EMT-transcription factors. Here we characterize major pathways regulating this atypical EMT through whole genome transcriptome profiling and molec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Parveen, Sana, Vedagiri, Dhiviya, Nair, Hitha Gopalan, Parthasarathy, Haripriya, Harshan, Krishnan Harinivas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562823/
https://ncbi.nlm.nih.gov/pubmed/28821798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09179-0
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