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Identification of the N-terminal transmembrane domain of StarD7 and its importance for mitochondrial outer membrane localization and phosphatidylcholine transfer

StarD7 facilitates phosphatidylcholine (PC) transfer to mitochondria, and is essential for mitochondrial homeostasis. However, the molecular mechanism for PC transfer by protein remains poorly understood. Herein, we describe a putative novel transmembrane (TM) domain C-terminal to the mitochondria-t...

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發表在:Sci Rep
Main Authors: Horibata, Yasuhiro, Ando, Hiromi, Satou, Motoyasu, Shimizu, Hiroaki, Mitsuhashi, Satomi, Shimizu, Yasuo, Itoh, Masahiko, Sugimoto, Hiroyuki
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562819/
https://ncbi.nlm.nih.gov/pubmed/28821867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09205-1
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