The phasevarion: A genetic system controlling coordinated, random switching of expression of multiple genes

Several host-adapted bacterial pathogens contain methyltransferases associated with type III restriction-modification (R-M) systems that are subject to reversible, high-frequency on/off switching of expression (phase variation). To investigate the role of phase-variable expression of R-M systems, we...

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Bibliographic Details
Main Authors: Srikhanta, Yogitha N., Maguire, Tina L., Stacey, Katryn J., Grimmond, Sean M., Jennings, Michael P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC556257/
https://ncbi.nlm.nih.gov/pubmed/15802471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501169102
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