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Activity-dependent NMDA receptor degradation mediated by retrotranslocation and ubiquitination
The extracellular N-terminal domain (NTD) is the largest region of NMDA receptors; however, biological roles for this ectodomain remain unknown. Here, we determined that the F-box protein, Fbx2, bound to high-mannose glycans of the NR1 ectodomain. F-box proteins specify ubiquitination by linking pro...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC556250/ https://ncbi.nlm.nih.gov/pubmed/15809437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501769102 |
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