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Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine

The gliotransmitter d-serine is released upon (S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate and metabotropic glutamate receptor stimulation, but the mechanisms involved are unknown. Here, by using a highly sensitive bioassay to continuously monitor extracellular d-serine levels, w...

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Main Authors: Mothet, Jean-Pierre, Pollegioni, Loredano, Ouanounou, Gilles, Martineau, Magalie, Fossier, Philippe, Baux, Gérard
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC556243/
https://ncbi.nlm.nih.gov/pubmed/15800046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408483102
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