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Maternal autoimmune antibodies alter the dendritic arbor and spine numbers in the infragranular layers of the cortex

An association between maternal IgG antibodies reactive against proteins in fetal brain and an outcome of autism in the child has been identified. Using a mouse model of prenatal intraventricular administration of autism-specific maternal IgG, we demonstrated that these antibodies produce behavioral...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Ariza, Jeanelle, Hurtado, Jesus, Rogers, Haille, Ikeda, Raymond, Dill, Michael, Steward, Craig, Creary, Donnay, Van de Water, Judy, Martínez-Cerdeño, Verónica
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562324/
https://ncbi.nlm.nih.gov/pubmed/28820892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183443
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