Impact of novel palmitoylated prolactin-releasing peptide analogs on metabolic changes in mice with diet-induced obesity

Analogs of anorexigenic neuropeptides, such as prolactin-releasing peptide (PrRP), have a potential as new anti-obesity drugs. In our previous study, palmitic acid attached to the N-terminus of PrRP enabled its central anorexigenic effects after peripheral administration. In this study, two linkers,...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Pražienková, Veronika, Holubová, Martina, Pelantová, Helena, Bugáňová, Martina, Pirník, Zdenko, Mikulášková, Barbora, Popelová, Andrea, Blechová, Miroslava, Haluzík, Martin, Železná, Blanka, Kuzma, Marek, Kuneš, Jaroslav, Maletínská, Lenka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562305/
https://ncbi.nlm.nih.gov/pubmed/28820912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183449
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