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Mice lacking Gpr37 exhibit decreased expression of the myelin-associated glycoprotein MAG and increased susceptibility to demyelination

GPR37 is an orphan G protein-coupled receptor that is predominantly expressed in the brain and found at particularly high levels in oligodendrocytes. GPR37 has been shown to exert effects on oligodendrocyte differentiation and myelination during development, but the molecular basis of these actions...

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Vydáno v:Neuroscience
Hlavní autoři: Smith, Brilee M., Giddens, Michelle M., Neil, Jessica, Owino, Sharon, Nguyen, TrangKimberly T., Duong, Duc, Li, Fengqiao, Hall, Randy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562287/
https://ncbi.nlm.nih.gov/pubmed/28642167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.06.006
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