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A simple answer to complex questions: C. elegans as an experimental model for examining the DNA damage response and disease genes

The genetic information is constantly challenged by genotoxic attacks. DNA repair mechanisms evolved early in evolution and recognize and remove the various lesions. A complex network of DNA damage responses (DDR) orchestrates a variety of physiological adaptations to the presence of genome instabil...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Rieckher, Matthias, Bujarrabal, Arturo, Doll, Markus A., Soltanmohammadi, Najmeh, Schumacher, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562273/
https://ncbi.nlm.nih.gov/pubmed/28463453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25979
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