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Evaluation of Safety in Exceeding Maximum Adult Doses of Commonly Used Second-Generation Antiepileptic Drugs in Pediatric Patients

OBJECTIVE: Pediatric patients often require larger doses of antiepileptic drug (AED) than adults in order to attain therapeutic serum concentrations and/or achieve seizure control. Safety and efficacy data are often extrapolated from adult literature; hence, optimal dosage may only be determined ane...

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Detalhes bibliográficos
Publicado no:J Pediatr Pharmacol Ther
Main Authors: Messinger, Mindl M., Misra, Sunita N., Clark, Gary D., DiCarlo, Shannon M.
Formato: Artigo
Idioma:Inglês
Publicado em: Pediatric Pharmacy Advocacy Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562204/
https://ncbi.nlm.nih.gov/pubmed/28943819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-22.4.256
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