HMGB1 regulates P-glycoprotein expression in status epilepticus rat brains via the RAGE/NF-κB signaling pathway

Overexpression of P-glycoprotein (P-gp) in the brain is an important mechanism involved in drug-resistant epilepsy (DRE). High-mobility group box 1 (HMGB1), an inflammatory cytokine, significantly increases following seizures and may be involved in upregulation of P-gp. However, the underlying mecha...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Xie, Yuan, Yu, Nian, Chen, Yan, Zhang, Kang, Ma, Hai-Yan, Di, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562060/
https://ncbi.nlm.nih.gov/pubmed/28627626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6772
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