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Adiposity Amplifies the Genetic Risk of Fatty Liver Disease Conferred by Multiple Loci

Complex traits arise from the interplay between genetic and environmental factors. The actions of these factors usually appear to be additive, and few compelling examples of gene-environment synergy have been documented. Here we show that adiposity significantly amplifies the effect of three sequenc...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Stender, Stefan, Kozlitina, Julia, Nordestgaard, Børge G., Tybjærg-Hansen, Anne, Hobbs, Helen H., Cohen, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562020/
https://ncbi.nlm.nih.gov/pubmed/28436986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3855
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