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Ultrasound-guided intratumoral delivery of doxorubicin from in situ forming implants in a hepatocellular carcinoma model

BACKGROUND: Hepatocellular carcinomas are frequently nonresponsive to systemically delivered drugs. Local delivery provides an alternative to systemic administration, maximizing the dose delivered to the tumor, achieving sustained elevated concentrations of the drug, while minimizing systemic exposu...

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Dettagli Bibliografici
Pubblicato in:Ther Deliv
Autori principali: Solorio, Luis, Wu, Hanping, Hernandez, Christopher, Gangolli, Mihika, Exner, Agata A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Future Science Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561990/
https://ncbi.nlm.nih.gov/pubmed/27010983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/tde-2015-0008
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