Filomicelles from aromatic diblock copolymers increase paclitaxel-induced tumor cell death and aneuploidy compared with aliphatic copolymers

AIM: In order to improve the delivery of aromatic drugs by micellar assemblies, and particularly by long and flexible filomicelles, aromatic groups were integrated into the hydrophobic block of a degradable diblock copolymer. MATERIALS & METHODS: Aromatic filomicelles were formed by self-directe...

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Gepubliceerd in:Nanomedicine (Lond)
Hoofdauteurs: Nair, Praful R, Karthick, SA, Spinler, Kyle R, Vakili, Mohammad R, Lavasanifar, Afsaneh, Discher, Dennis E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Future Medicine Ltd 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561966/
https://ncbi.nlm.nih.gov/pubmed/27177319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2016-0007
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