Combined action of MK-801 and ceftriaxone impairs the acquisition and reinstatement of morphine-induced conditioned place preference, and delays morphine extinction in rats

OBJECTIVE: It is well established that glutamate and its receptors, particularly the N-methyl-D-aspartate receptor (NMDAR), play a significant role in addiction and that the inhibition of glutamatergic hyperfunction reduces addictive behaviors in experimental animals. Specifically, NMDAR antagonists...

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Pubblicato in:Neurosci Bull
Autori principali: Fan, Yaodong, Niu, Haichen, Rizak, Joshua D., Li, Ling, Wang, Guimei, Xu, Liqi, Ren, He, Lei, Hao, Yu, Hualin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561921/
https://ncbi.nlm.nih.gov/pubmed/23054634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-012-1269-8
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