Amyloid-β depresses excitatory cholinergic synaptic transmission in Drosophila

OBJECTIVE: Decline, disruption, or alterations of nicotinic cholinergic mechanisms contribute to cognitive dysfunctions like Alzheimer’s disease (AD). Although amyloid-β (Aβ) aggregation is a pathological hallmark of AD, the mechanisms by which Aβ peptides modulate cholinergic synaptic transmission...

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Bibliografski detalji
Izdano u:Neurosci Bull
Glavni autori: Fang, Liqun, Duan, Jingjing, Ran, Dongzhi, Fan, Zihao, Yan, Ying, Huang, Naya, Gu, Huaiyu, Zhu, Yulan
Format: Artigo
Jezik:Inglês
Izdano: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2012
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561919/
https://ncbi.nlm.nih.gov/pubmed/23054636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-012-1267-x
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