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Evolving lessons on nanomaterial-coated viral vectors for local and systemic gene therapy

Viral vectors are promising gene carriers for cancer therapy. However, virus-mediated gene therapies have demonstrated insufficient therapeutic efficacy in clinical trials due to rapid dissemination to nontarget tissues and to the immunogenicity of viral vectors, resulting in poor retention at the d...

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Detalhes bibliográficos
Publicado no:Nanomedicine (Lond)
Main Authors: Kasala, Dayananda, Yoon, A-Rum, Hong, Jinwoo, Kim, Sung Wan, Yun, Chae-Ok
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561791/
https://ncbi.nlm.nih.gov/pubmed/27348247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2016-0060
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