Impaired calcium sensing distinguishes primary hyperparathyroidism (PHPT) patients with low bone mineral density

CONTEXT: A subset of PHPT patients exhibit a more severe disease phenotype characterized by bone loss, fractures, recurrent nephrolithiasis, and other dysfunctions, but the underlying reasons for this disparity in clinical presentation remain unknown. OBJECTIVE: We sought to identify new mechanistic...

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Publicat a:Metabolism
Autors principals: Weber, Thomas J., Koh, James, Thomas, Samantha M., Hogue, Joyce A., Scheri, Randall P., Roman, Sanziana A., Sosa, Julie A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561769/
https://ncbi.nlm.nih.gov/pubmed/28764845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2017.06.004
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