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Computational model and microfluidic platform for the investigation of paracrine and autocrine signaling in mouse embryonic stem cells()

Autocrine and paracrine signaling mechanisms are traditionally difficult to study due to the recursive nature of the process and the sub-micromolar concentrations involved. This has proven to be especially limiting in the study of embryonic stem cells that might rely on such signaling for viability,...

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Detalhes bibliográficos
Publicado no:Mol Biosyst
Main Authors: Ellison, David, Munden, Alex, Levchenko, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561740/
https://ncbi.nlm.nih.gov/pubmed/19668866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b905602e
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