Population Pharmacokinetic Analysis of Bortezomib in Pediatric Leukemia Patients: Model‐Based Support for Body Surface Area‐Based Dosing Over the 2‐ to 16‐Year Age Range

This population analysis described the pharmacokinetics of bortezomib after twice‐weekly, repeat‐dose, intravenous administration in pediatric patients participating in 2 clinical trials: the phase 2 AALL07P1 (NCT00873093) trial in relapsed acute lymphoblastic leukemia and the phase 3 AAML1031 (NCT0...

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Foilsithe in:J Clin Pharmacol
Main Authors: Hanley, Michael J., Mould, Diane R., Taylor, Timothy J., Gupta, Neeraj, Suryanarayan, Kaveri, Neuwirth, Rachel, Esseltine, Dixie‐Lee, Horton, Terzah M., Aplenc, Richard, Alonzo, Todd A., Lu, Xiaomin, Milton, Ashley, Venkatakrishnan, Karthik
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2017
Ábhair:
Pediatric Pharmacology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561493/
https://ncbi.nlm.nih.gov/pubmed/28419486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.906
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