Anticollagen type II antibodies are associated with an acute onset rheumatoid arthritis phenotype and prognosticate lower degree of inflammation during 5 years follow-up

OBJECTIVE: Antifibrillar collagen type II (anti-CII) antibody-positive patients with rheumatoid arthritis (RA) have early but not late signs of increased inflammation and joint erosions. We wanted to replicate this in a large RA cohort, and to relate to human leukocyte antigen (HLA)-DRB1* alleles. M...

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Vydáno v:Ann Rheum Dis
Hlavní autoři: Manivel, Vivek Anand, Mullazehi, Mohammed, Padyukov, Leonid, Westerlind, Helga, Klareskog, Lars, Alfredsson, Lars, Saevarsdottir, Saedis, Rönnelid, Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2017
Témata:
Clinical and Epidemiological Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561381/
https://ncbi.nlm.nih.gov/pubmed/28336519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210873
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