Discovery of Lysine Hydroxylases in the Clavaminic Acid Synthase-Like Superfamily for Efficient Hydroxylysine Bioproduction

Hydroxylation via C—H bond activation in the absence of any harmful oxidizing reagents is technically difficult in modern chemistry. In this work, we attempted to generate pharmaceutically important hydroxylysine from readily available l-lysine with l-lysine hydroxylases from diverse microorganisms....

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Vydáno v:Appl Environ Microbiol
Hlavní autoři: Hara, Ryotaro, Yamagata, Kai, Miyake, Ryoma, Kawabata, Hiroshi, Uehara, Hisatoshi, Kino, Kuniki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Enzymology and Protein Engineering
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561292/
https://ncbi.nlm.nih.gov/pubmed/28667106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00693-17
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