PREDICTING GENE EXPRESSION IN MASSIVELY PARALLEL REPORTER ASSAYS: A COMPARATIVE STUDY

In many human diseases, associated genetic changes tend to occur within non-coding regions, whose effect might be related to transcriptional control. A central goal in human genetics is to understand the function of such non-coding regions: Given a region that is statistically associated with change...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Kreimer, Anat, Zeng, Haoyang, Edwards, Matthew D., Guo, Yuchun, Tian, Kevin, Shin, Sunyoung, Welch, Rene, Wainberg, Michael, Mohan, Rahul, Sinnott-Armstrong, Nicholas A., Li, Yue, Eraslan, Gökcen, AMIN, Talal Bin, Goke, Jonathan, Mueller, Nikola S., Kellis, Manolis, Kundaje, Anshul, Beer, Michael A, Keles, Sunduz, Gifford, David K., Yosef, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560998/
https://ncbi.nlm.nih.gov/pubmed/28220625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23197
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