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Cross-reactivity, antivenomics, and neutralization of toxic activities of Lachesis venoms by polyspecific and monospecific antivenoms

BACKGROUND: Bothrops, Crotalus and Lachesis represent the most medically relevant genera of pitvipers in Central and South America. Similarity in venom phenotype and physiopathological profile of envenomings caused by the four nominal Lachesis species led us to hypothesize that an antivenom prepared...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Madrigal, Marvin, Pla, Davinia, Sanz, Libia, Barboza, Elexandra, Arroyo-Portilla, Cynthia, Corrêa-Netto, Carlos, Gutiérrez, José María, Alape-Girón, Alberto, Flores-Díaz, Marietta, Calvete, Juan J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560760/
https://ncbi.nlm.nih.gov/pubmed/28787445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005793
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