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MCK1 is a novel regulator of myo-inositol phosphate synthase (MIPS) that is required for inhibition of inositol synthesis by the mood stabilizer valproate

Myo-inositol, the precursor of all inositol compounds, is essential for the viability of eukaryotes. Identifying the factors that regulate inositol homeostasis is of obvious importance to understanding cell function and the pathologies underlying neurological and metabolic resulting from perturbatio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Wenxi, Daniel, Joshua, Mehta, Dhara, Maddipati, Krishna Rao, Greenberg, Miriam L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560674/
https://ncbi.nlm.nih.gov/pubmed/28817575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182534
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