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Reverse recruitment: The Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation

The recruitment model for gene activation presumes that DNA is a platform on which the requisite components of the transcriptional machinery are assembled. In contrast to this idea, we show here that Rap1/Gcr1/Gcr2 transcriptional activation in yeast cells occurs through a large anchored protein pla...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Menon, Balaraj B., Sarma, Nayan J., Pasula, Satish, Deminoff, Stephen J., Willis, Kristine A., Barbara, Kellie E., Andrews, Brenda, Santangelo, George M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15817685/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0501768102
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