Development of a new analog of SGK1 inhibitor and its evaluation as a therapeutic molecule of colorectal cancer

Colorectal cancer (CRC) is one of the most leading causes of cancer-related death worldwide. The serum and glucocorticoid inducible kinase SGK1 is highly expressed and involved in several tumors. GSK650394, a SGK1 inhibitor, has been proved to be effective in impeding tumor growth in vitro. In this...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Liang, Xuchun, Lan, Chunling, Zhou, Jinzhe, Fu, Wencheng, Long, Xuesha, An, Yu, Jiao, Guanming, Wang, Kejin, Li, Yongqin, Xu, Jiahong, Huang, Qi, Xu, Bin, Xiao, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560143/
https://ncbi.nlm.nih.gov/pubmed/28819428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19566
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