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Congenital diaphragmatic hernias: from genes to mechanisms to therapies

Congenital diaphragmatic hernias (CDHs) and structural anomalies of the diaphragm are a common class of congenital birth defects that are associated with significant morbidity and mortality due to associated pulmonary hypoplasia, pulmonary hypertension and heart failure. In ∼30% of CDH patients, gen...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Kardon, Gabrielle, Ackerman, Kate G., McCulley, David J., Shen, Yufeng, Wynn, Julia, Shang, Linshan, Bogenschutz, Eric, Sun, Xin, Chung, Wendy K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560060/
https://ncbi.nlm.nih.gov/pubmed/28768736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028365
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