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Wnt signalling controls the response to mechanical loading during zebrafish joint development

Joint morphogenesis requires mechanical activity during development. Loss of mechanical strain causes abnormal joint development, which can impact long-term joint health. Although cell orientation and proliferation are known to shape the joint, dynamic imaging of developing joints in vivo has not be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Brunt, Lucy H., Begg, Katie, Kague, Erika, Cross, Stephen, Hammond, Chrissy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560048/
https://ncbi.nlm.nih.gov/pubmed/28684625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153528
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