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Genetic polymorphisms of lncRNA-p53 regulatory network genes are associated with concurrent chemoradiotherapy toxicities and efficacy in nasopharyngeal carcinoma patients

The relevance of the transcription factor p53 in cancer is inarguable, and numerous lncRNAs are involved in the p53 regulatory network as either regulators or effectors, triggering a transcriptional response that causes either cell arrest or apoptosis following DNA damage in a p53-dependent manner....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Youhong, Guo, Zhen, Zhao, Yu, Jin, Yi, An, Liang, Wu, Bin, Liu, Zhaoqian, Chen, Xiaoping, Chen, Xiang, Zhou, Honghao, Wang, Hui, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559481/
https://ncbi.nlm.nih.gov/pubmed/28814798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08890-2
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