Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function

BACKGROUND: Parasites exploit sophisticated strategies to evade host immunity that require both adaptation of existing genes and evolution of new gene families. We have addressed this question by testing the immunological function of novel genes from helminth parasites, in which conventional transge...

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Autori principali: Gomez-Escobar, Natalia, Bennett, Clare, Prieto-Lafuente, Lidia, Aebischer, Toni, Blackburn, Clare C, Maizels, Rick M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC555940/
https://ncbi.nlm.nih.gov/pubmed/15788098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-3-8
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