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Perioperative COX-2 and β-adrenergic blockade improves metastatic biomarkers in breast cancer patients in a phase-II randomized trial

BACKGROUND: Translational studies suggest that excess perioperative release of catecholamines and prostaglandins may facilitate metastasis and reduce disease-free survival. This trial tested the combined perioperative blockade of these pathways in breast cancer patients. METHODS: In a randomized pla...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Shaashua, Lee, Shabat-Simon, Maytal, Haldar, Rita, Matzner, Pini, Zmora, Oded, Shabtai, Moshe, Sharon, Eran, Allweis, Tanir, Barshak, Iris, Hayman, Lucile, Arevalo, Jesusa, Ma, Jeffrey, Horowitz, Maya, Cole, Steven, Ben-Eliyahu, Shamgar
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559335/
https://ncbi.nlm.nih.gov/pubmed/28490464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0152
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